Bringing together those passionately pursuing the future of healthcare with Mayo Clinic doctors, researchers and scientists.

One and Two Discovery Square are the epicenter of what’s next in healthcare. Here, visionary start-ups, researchers, educators and companies collaborate with the esteemed Mayo Clinic and one another to advance biomedical technology and treatments of tomorrow.

When you locate at One or Two Discovery Square, you will be in the heart of Destination Medical Center’s Discovery Square District. Destination Medical Center is a 20-year, $5.6 billion economic development engine creating a global destination for health and wellness with Mayo Clinic and innovation at its core. You will be steps from Mayo Clinic’s 1.5 million square feet of research and lab space, with access to Mayo Clinic core services and Mayo Clinic Ventures, which can help advance your intellectual property and business.

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Flexible spaces tailored to life science operations.

Designed for collaboration, One and Two Discovery Square are state-of-the-art buildings thoughtfully designed to fuel collective energy, creativity and problem-solving, and expedite the time from bench to bedside. Onsite programming fosters interaction and moments of structured serendipity among tenants and researchers, physicians and business leaders from the greater Rochester community.

Mortenson is now leasing Two Discovery Square for immediate occupancy. The first WiredScored-Certified Building in Rochester, Two Discovery Square offers your business: 

Equally important, you will be steps from the Mayo Clinic, clinicians, researchers and businesses with which you can collaborate. Current campus tenants include the likes of EPIC, Motion Medical by Boston Scientific, Wuxi Diagnostics, novavita thera, Philips and several Mayo Clinic start-up ventures.

Amenities and professional programming foster structured serendipity.

One and Two Discovery Square are the hub of activity for the Discovery Square District. With Café Steam – the best coffee in Rochester! – ongoing meetups, thought-leader discussions and happy hour events, your team will love working here. You will be a short walk from retail, restaurants, green space and newly built downtown residential buildings.